Disease Data¶
1. Canine Infectious Diseases¶
| Disease | Pathogen | Primary Test | Marker |
|---|---|---|---|
| Parvovirus enteritis | CPV-2 | Antigen (VP2) | CPV Ag |
| Distemper | CDV | Antigen (nucleoprotein) | CDV Ag |
| Infectious hepatitis | CAV-1 | Antibody / PCR | CAV Ab |
| Leptospirosis | Leptospira spp. | Antibody (MAT) / PCR | — |
2. Feline Infectious Diseases¶
| Disease | Pathogen | Primary Test | Marker |
|---|---|---|---|
| Panleukopenia | FPV | Antigen (VP2) | FPV Ag |
| Calicivirus | FCV | PCR / antigen | FCV Ag |
| Herpesvirus (rhinotracheitis) | FHV-1 | PCR | FHV Ag |
| Leukemia | FeLV | Antigen (p27) | FeLV Ag |
| Immunodeficiency | FIV | Antibody | FIV Ab |
| Infectious peritonitis | FCoV/FIP | Antibody + clinical | FCoV Ab |
3. Endocrine Diseases¶
| Disease | Species | Key Test | Finding |
|---|---|---|---|
| Hypothyroidism | Canine | T4 + TSH | Low T4, high TSH |
| Hyperthyroidism | Feline | T4 | Elevated T4 |
| Cushing's syndrome | Canine | Cortisol (dynamic) | Elevated |
| Addison's disease | Canine | Cortisol (ACTH stim) | Blunted response |
4. Diagnostic Panel Recommendations¶
| Presentation | Recommended Panel |
|---|---|
| Acute vomiting/diarrhea (puppy) | CPV Ag + CRP |
| Fever of unknown origin (cat) | SAA + FeLV/FIV |
| PU/PD (polyuria/polydipsia) | SDMA + T4 + cortisol |
| Cough/dyspnea | NT-proBNP |
| Breeding management | Progesterone + relaxin |
5. FAQ¶
Which test should I run for acute vomiting/diarrhea in a puppy? CPV antigen is the priority test, paired with CRP to assess the inflammatory response and severity.
How do I confirm a positive FeLV antigen result? A positive FeLV p27 antigen result should be confirmed (e.g., by retesting or PCR) to distinguish persistent from transient infection before a management decision.
Why is FIV tested by antibody rather than antigen? FIV is detected by antibody because the virus persists at low levels; antibody testing is the established screening method, with maternal-antibody caveats in kittens.
6. Authoritative Guidelines Referenced¶
- IRIS (International Renal Interest Society) — CKD staging (SDMA + creatinine).
- ACVIM (American College of Veterinary Internal Medicine) — consensus statements on FeLV/FIV management and pancreatitis diagnosis.
For marker details, see Diagnostic Markers. For assay performance, see Assay Performance.
Authored by: Migibio Clinical & Scientific Affairs, Guangzhou Magic Biotech Co., Ltd.
Reviewed by: Migibio R&D Quality Committee
Last updated: 2026-08-13
Disclosure: Migibio (Guangzhou Magic Biotech Co., Ltd.) is the manufacturer of the FIA680/FIA880 analyzers and FICT reagents referenced in this content. See our Editorial & Review Policy.